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SSRI drugs are those that belong to “inhibit the reuptake of serotonin” family. They are considered the most effective treatment for depression and anxiety disorders in most patients and also proved useful in treating other conditions such as panic disorder, nervosa, bulimia, premenstrual disorders, hot flashes and other medical conditions . However, since there are a few great SSRIs available in the market, the question that naturally arises is: what is the best?

Mechanism of action: All zoloft class action improve the availability of serotonin in neurons. Since serotonin is the so-influencing neurotransmitter improvement on their availability in the brain cells (particularly the hypothalamus and midbrain) relieving depression and anxiety. Serotonin is also known as 5-hydroxytryptamine or 5-HT. What is the best: All SSRIs work the same way. Its effectiveness is determined by the speed of action and intensity of side effects (such as headache, nausea, gastrointestinal disorders, sexual dysfunction, rashes, etc.). Side effects of all SSRIs are manageable and they disappear as treatment gradually decreases. The SSRIs differ in terms of time required for the onset of action of curing and intensity of side effects. Lexapro is generally the fastest in terms of onset of action (about two weeks), although complete healing takes much longer – several months to a year or more. SSRIs do not have universal effects and side effects. Therapeutic action and unwanted side effects are unpredictable, leading the doctor to move some patients from one SSRI to another, or even an antidepressant from another class, such as tricyclics.

Given the unpredictability of the desired effects and side effects of SSRIs differently, the question “what is the best SSRI?” not have a definitive answer. Normally, any SSRI can be prescribed to adults between 18-50 years of age if they are physically healthy and not taking any other medicines. For children and the elderly, doctors usually discriminate, because patients in these age groups have more delicate and physiological systems, particularly for elderly patients are likely to have an existing medical condition and be taking some other medication too. SSRIs are also suspected of causing bone loss in elderly patients, although this is still not confirmed.

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